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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
32.73
Human Site:
S121
Identified Species:
45
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
S121
K
S
A
S
Y
K
Y
S
E
E
A
N
N
L
I
Chimpanzee
Pan troglodytes
XP_509950
468
54427
S121
K
S
A
S
Y
K
Y
S
E
E
A
N
N
L
I
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
S121
K
S
A
S
Y
K
Y
S
E
E
A
N
N
L
I
Dog
Lupus familis
XP_547813
468
54343
S121
K
S
A
S
Y
K
Y
S
E
V
A
N
N
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
S121
K
S
A
S
Y
K
Y
S
E
E
A
N
R
I
E
Rat
Rattus norvegicus
Q8R4A1
464
54000
S121
K
S
A
S
Y
K
Y
S
K
E
A
N
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
S118
K
S
S
S
Y
K
Y
S
E
E
A
N
T
L
T
Chicken
Gallus gallus
XP_421473
463
52908
S119
R
S
A
G
Y
K
Y
S
E
E
A
N
S
H
A
Frog
Xenopus laevis
Q6DD71
465
53720
E117
P
P
G
F
K
Y
T
E
E
A
N
H
V
H
E
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
S113
K
S
S
S
Y
K
Y
S
E
K
A
S
H
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
E130
K
D
K
G
E
H
K
E
K
A
A
F
K
Y
T
Honey Bee
Apis mellifera
XP_623933
471
55049
V125
K
G
D
I
L
R
N
V
H
F
N
E
N
P
M
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
E115
R
R
N
A
V
N
M
E
A
A
A
V
K
E
E
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
K538
K
E
E
S
N
E
N
K
Y
S
S
D
S
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
L144
K
K
P
F
V
P
G
L
P
S
D
D
L
K
C
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
G126
Y
W
Q
P
E
I
L
G
S
F
N
N
D
T
M
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
L114
E
V
W
R
A
K
E
L
G
K
L
E
G
P
R
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
80
66.6
6.6
60
N.A.
13.3
13.3
6.6
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
80
13.3
86.6
N.A.
20
26.6
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
6
6
0
0
0
6
18
65
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
0
6
6
0
0
0
0
0
0
0
6
12
6
6
0
% D
% Glu:
6
6
6
0
12
6
6
18
53
42
0
12
0
6
24
% E
% Phe:
0
0
0
12
0
0
0
0
0
12
0
6
0
0
0
% F
% Gly:
0
6
6
12
0
0
6
6
6
0
0
0
6
0
0
% G
% His:
0
0
0
0
0
6
0
0
6
0
0
6
6
12
0
% H
% Ile:
0
0
0
6
0
6
0
0
0
0
0
0
0
6
24
% I
% Lys:
71
6
6
0
6
59
6
6
12
12
0
0
12
6
6
% K
% Leu:
0
0
0
0
6
0
6
12
0
0
6
0
12
36
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
12
% M
% Asn:
0
0
6
0
6
6
12
0
0
0
18
53
30
6
0
% N
% Pro:
6
6
6
6
0
6
0
0
6
0
0
0
0
12
0
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
6
0
6
0
6
0
0
0
0
0
0
6
0
6
% R
% Ser:
0
53
12
53
0
0
0
53
6
12
6
6
12
0
0
% S
% Thr:
0
0
0
0
0
0
6
0
0
0
0
0
6
6
18
% T
% Val:
0
6
0
0
12
0
0
6
0
6
0
6
6
0
0
% V
% Trp:
0
6
6
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
53
6
53
0
6
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _